GPR157

GPR157
Identifiers
Aliases	GPR157, G protein-coupled receptor 157
External IDs	MGI: 2442046; HomoloGene: 18573; GeneCards: GPR157; OMA:GPR157 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	9,129,102 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	150,190,384 bp
RNA expression pattern
	Top expressed in
	vastus lateralis muscle; ; skin of arm; ; gums; ; gingival epithelium; ; Skeletal muscle tissue of biceps brachii; ; oral cavity; ; Skeletal muscle tissue of rectus abdominis; ; skin of thigh; ; tibialis anterior muscle; ; nasal epithelium;
	Top expressed in
	muscle of thigh; ; quadriceps femoris muscle; ; muscle tissue; ; skeletal muscle tissue; ; granulocyte; ; lip; ; heart; ; zone of skin; ; yolk sac; ; esophagus;
	More reference expression data
	n/a
Gene ontology
Molecular function	transmembrane signaling receptor activity; signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane; ciliary membrane; cell projection;
Biological process	cell surface receptor signaling pathway; signal transduction; G protein-coupled receptor signaling pathway; circadian behavior; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; radial glial cell differentiation; multicellular organism development; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	80045
	269604
	ENSG00000180758
	ENSMUSG00000047875
	Q5UAW9
	Q8C206
	NM_024980
	NM_177366
	NP_079256
	NP_796340
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 157 is a protein that in humans is encoded by the GPR157 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000180758 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000047875 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (Jan 2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.
^ "Entrez Gene: GPR157 G protein-coupled receptor 157".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Takeo Y, Kurabayashi N, Nguyen MD, Sanada K, et al. (2016). "The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway". Scientific Reports. 6: 25180–92. Bibcode:2016NatSR...625180T. doi:10.1038/srep25180. PMC 4855140. PMID 27142930.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000180758 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000047875 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10574461-5] Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (Jan 2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.

[entrez-6] "Entrez Gene: GPR157 G protein-coupled receptor 157".

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References

Further reading