A | B | C | D | E | F | G | H | CH | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9
![]() Sample of copper naproxen in a glass vial
| |
![]() | |
Names | |
---|---|
Other names
Copper(II) 6-methoxy-a-methyl-2-naphthaleneacetate
| |
Identifiers | |
Properties | |
C28H26CuO6 | |
Molar mass | 522.056 g·mol−1 |
Appearance | Green solid |
Solubility | Soluble in methanol, 1,4-dioxane,[1] DMSO, DMF[2] |
Related compounds | |
Related compounds
|
Copper aspirinate Copper ibuprofenate |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
|
Copper naproxen is a chemical complex of copper2+ chelated with the anti-inflammatory drug naproxen.[1] Copper complexes of NSAIDs like naproxen have been shown to have greater anti-inflammatory properties than the base drug.[3][2]
Copper naproxen can by found as a monohydrate, and it can form complexes with other organic molecules such as nicotinyl alcohol, 3-methylpyridine, and caffeine.[1][4][5]
Preparation
Copper naproxen is prepared by reacting sodium naproxen with a copper(II) salt such as copper(II) sulfate.[1]
References
- ^ a b c d Melnı́k, Milan; Macásková, Lubov; Holloway, Clive E; Mrozinski, Jerzy; Kalin’ska, Bozena (March 2000). "Spectral and magnetic properties of copper(II) naproxenates". Inorganica Chimica Acta. 299 (2): 284–287. doi:10.1016/S0020-1693(99)00504-6.
- ^ a b Dimiza, Filitsa; Perdih, Franc; Tangoulis, Vassilis; Turel, Iztok; Kessissoglou, Dimitris P.; Psomas, George (March 2011). "Interaction of copper(II) with the non-steroidal anti-inflammatory drugs naproxen and diclofenac: Synthesis, structure, DNA- and albumin-binding". Journal of Inorganic Biochemistry. 105 (3): 476–489. doi:10.1016/j.jinorgbio.2010.08.013.
- ^ Sorenson, John R.J. (1989), 6 Copper Complexes Offer a Physiological Approach to Treatment of Chronic Diseases, Progress in Medicinal Chemistry, vol. 26, Elsevier, pp. 437–568, doi:10.1016/s0079-6468(08)70246-7, ISBN 978-0-444-81038-0, retrieved 2022-04-10
- ^ Caglar, Sema; Adiguzel, Ekrem; Sariboga, Bahtiyar; Temel, Ersin; Buyukgungor, Orhan (2014-02-16). "Mono and dinuclear copper(II) naproxenato complexes containing 3-picoline and 4-picoline: synthesis, structure, properties, catechol oxidase, and antimicrobial activities". Journal of Coordination Chemistry. 67 (4): 670–683. doi:10.1080/00958972.2014.891198. ISSN 0095-8972. S2CID 96991445.
- ^ Abuhijleh, A. Latif; Khalaf, Juhienah (September 2010). "Copper (II) complexes of the anti-inflammatory drug naproxen and 3-pyridylmethanol as auxiliary ligand. Characterization, superoxide dismutase and catecholase – mimetic activities". European Journal of Medicinal Chemistry. 45 (9): 3811–3817. doi:10.1016/j.ejmech.2010.05.031. PMID 20605277.
Text je dostupný za podmienok Creative Commons Attribution/Share-Alike License 3.0 Unported; prípadne za ďalších podmienok. Podrobnejšie informácie nájdete na stránke Podmienky použitia.
Antropológia
Aplikované vedy
Bibliometria
Dejiny vedy
Encyklopédie
Filozofia vedy
Forenzné vedy
Humanitné vedy
Knižničná veda
Kryogenika
Kryptológia
Kulturológia
Literárna veda
Medzidisciplinárne oblasti
Metódy kvantitatívnej analýzy
Metavedy
Metodika
Text je dostupný za podmienok Creative
Commons Attribution/Share-Alike License 3.0 Unported; prípadne za ďalších
podmienok.
Podrobnejšie informácie nájdete na stránke Podmienky
použitia.
www.astronomia.sk | www.biologia.sk | www.botanika.sk | www.dejiny.sk | www.economy.sk | www.elektrotechnika.sk | www.estetika.sk | www.farmakologia.sk | www.filozofia.sk | Fyzika | www.futurologia.sk | www.genetika.sk | www.chemia.sk | www.lingvistika.sk | www.politologia.sk | www.psychologia.sk | www.sexuologia.sk | www.sociologia.sk | www.veda.sk I www.zoologia.sk