This is a list of gene families or gene complexes, i.e. sets of genes which are related ancestrally and often serve similar biological functions. These gene families typically encode functionally related proteins, and sometimes the term gene families is a shorthand for the sets of proteins that the genes encode. They may or may not be physically adjacent on the same chromosome.

Regulatory protein gene families

• 14-3-3 protein family
• Achaete-scute complex (neuroblast formation)
• FOX proteins (forkhead box proteins)
• Families containing homeobox domains
  • DLX gene family
  • Hox gene family
  • POU family
• Krüppel-type zinc finger (ZNF)
• MADS-box gene family
• NOTCH2NL
• P300-CBP coactivator family
• SOX gene family

Immune system proteins

• Immunoglobulin superfamily
• Major histocompatibility complex (MHC)

Motor proteins

• Dynein
• Kinesin
• Myosin

Signal transducing proteins

• G-proteins
• MAP Kinase
• Olfactory receptor
• Peroxiredoxin
• Receptor tyrosine kinases

Transporters

• ABC transporters
• Antiporter
• Aquaporins

Other families

See also

• Protein family
• Housekeeping gene