Oxidized cellulose

Oxidized cellulose
Clinical data
ATC code	B02BC02 (WHO) ;
Identifiers
ChemSpider	none;
UNII	44AIH82TSC;
	(what is this?) (verify)

Oxidized cellulose is a water-insoluble derivative of cellulose. It can be produced from cellulose by the action of an oxidizing agent, such as chlorine, hydrogen peroxide, peracetic acid, chlorine dioxide, nitrogen dioxide, persulfates, permanganate, dichromate-sulfuric acid, hypochlorous acid, hypohalites or periodates and a variety of metal catalysts.^[1] Oxidized cellulose may contain carboxylic acid, aldehyde, and/or ketone groups, in addition to the original hydroxyl groups of the starting material, cellulose, depending on the nature of the oxidant and reaction conditions.^[2]

It is an antihemorrhagic.^[3] It works both by absorbing the blood (similar to a cotton ball)^[4] and by triggering the contact activation system. It is poorly absorbed and may cause healing complications postoperatively.^[5]

References

^ Collinson SR, Thielemans W (August 2010). "The catalytic oxidation of biomass to new materials focusing on starch, cellulose and lignin" (PDF). Coordination Chemistry Reviews. 254 (15–16): 1854–1870. doi:10.1016/j.ccr.2010.04.007.
^ US 5780618, Banker GS, Kumar V, "Oxidized cellulose", issued 14 July 1998, assigned to Biocontrol Inc.
^ Oto A, Remer EM, O'Malley CM, Tkach JA, Gill IS (June 1999). "MR characteristics of oxidized cellulose (Surgicel)". AJR. American Journal of Roentgenology. 172 (6): 1481–1484. doi:10.2214/ajr.172.6.10350276. PMID 10350276.
^ "Oxidised Cellulose". Advanced Medical Solutions Group plc. 30 November 2023.
^ Resnik RR (2018). "Intraoperative Complications". In Resnik RR, Misch CE (eds.). Misch's Avoiding Complications in Oral Implantology. pp. 267–293. doi:10.1016/B978-0-323-37580-1.00007-X. ISBN 978-0-323-37580-1.

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[collinson-catox-1] Collinson SR, Thielemans W (August 2010). "The catalytic oxidation of biomass to new materials focusing on starch, cellulose and lignin" (PDF). Coordination Chemistry Reviews. 254 (15–16): 1854–1870. doi:10.1016/j.ccr.2010.04.007.

[2] US 5780618, Banker GS, Kumar V, "Oxidized cellulose", issued 14 July 1998, assigned to Biocontrol Inc.

[pmid10350276-3] Oto A, Remer EM, O'Malley CM, Tkach JA, Gill IS (June 1999). "MR characteristics of oxidized cellulose (Surgicel)". AJR. American Journal of Roentgenology. 172 (6): 1481–1484. doi:10.2214/ajr.172.6.10350276. PMID 10350276.

[4] "Oxidised Cellulose". Advanced Medical Solutions Group plc. 30 November 2023.

[5] Resnik RR (2018). "Intraoperative Complications". In Resnik RR, Misch CE (eds.). Misch's Avoiding Complications in Oral Implantology. pp. 267–293. doi:10.1016/B978-0-323-37580-1.00007-X. ISBN 978-0-323-37580-1.

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[2]

[3]

[4]

[5]

Clinical data
ATC code	B02BC02 (WHO)
Identifiers
ChemSpider	none
UNII	44AIH82TSC
^NY (what is this?) (verify)

See also

References