Thonzonium bromide

Thonzonium bromide
Names
	Preferred IUPAC name N-(2-{(pyrimidin-2-yl)amino}ethyl)-N,N-dimethylhexadecan-1-aminium bromide
Identifiers
CAS Number	553-08-2 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1200883 ;
ChemSpider	10631 ;
ECHA InfoCard	100.008.212
PubChem CID	11102;
UNII	JI2B19CR0R ;
CompTox Dashboard (EPA)	DTXSID1045326 ;
	InChI InChI=1S/C32H55N4O.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27-36(2,3)28-26-35(32-33-24-19-25-34-32)29-30-20-22-31(37-4)23-21-30;/h19-25H,5-18,26-29H2,1-4H3;1H/q+1;/p-1 Key: WBWDWFZTSDZAIG-UHFFFAOYSA-M ;
	SMILES .O(c1ccc(cc1)CN(c2ncccn2)CC(CCCCCCCCCCCCCCCC)(C)C)C;
Properties
Chemical formula	C32H55BrN4O
Molar mass	591.723 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). verify (what is ?) Infobox references

Thonzonium bromide is a monocationic detergent.^[1] A solution of it is thus a surfactant and a detergent that promotes tissue contact by dispersion and penetration of the cellular debris and exudate of the containing solution.^[2]

It is used in cortisporin-TC ear drops to help penetration of active ingredients through cellular debris for its antibacterial action.^[3]^[4]

References

^ "Thonzonium bromide". Long Island University. Retrieved 2023-01-02.
^ "Otic Antibiotics Review 2009" (PDF). Otic Antibiotics Review. 6 (1): 11. 2009-12-15. Archived (PDF) from the original on 2023-01-03. Retrieved 2023-01-03 – via Nevada Department of Health and Human Services.
^ "Cortisporin-TC: Indications, Side Effects, Warnings". Drugs.com. 2022-10-15. Archived from the original on 2023-01-03. Retrieved 2023-01-03.
^ "CORTISPORIN-TC- colistin sulfate, neomycin sulfate, thonzonium bromide and hydrocortisone acetate suspension" (PDF). Food and Drug Administration. 2019. Archived (PDF) from the original on 2023-01-03. Retrieved 2023-01-02.

Zdroj:https://en.wikipedia.org?pojem=Thonzonium_bromide
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[1] "Thonzonium bromide". Long Island University. Retrieved 2023-01-02.

[2] "Otic Antibiotics Review 2009" (PDF). Otic Antibiotics Review. 6 (1): 11. 2009-12-15. Archived (PDF) from the original on 2023-01-03. Retrieved 2023-01-03 – via Nevada Department of Health and Human Services.

[3] "Cortisporin-TC: Indications, Side Effects, Warnings". Drugs.com. 2022-10-15. Archived from the original on 2023-01-03. Retrieved 2023-01-03.

[4] "CORTISPORIN-TC- colistin sulfate, neomycin sulfate, thonzonium bromide and hydrocortisone acetate suspension" (PDF). Food and Drug Administration. 2019. Archived (PDF) from the original on 2023-01-03. Retrieved 2023-01-02.

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v t e Xenobiotic-sensing receptor modulators
CARTooltip Constitutive androstane receptor	Agonists: 6,7-Dimethylesculetin Amiodarone Artemisinin Benfuracarb Carbamazepine Carvedilol Chlorpromazine Chrysin CITCO Clotrimazole Cyclophosphamide Cypermethrin DHEA (prasterone) Efavirenz Ellagic acid Griseofulvin Methoxychlor Mifepristone Nefazodone Nevirapine Nicardipine Octicizer Permethrin Phenobarbital Phenytoin Pregnanedione (5β-dihydroprogesterone) Reserpine TCPOBOP Telmisartan Tolnaftate Troglitazone Valproic acid Antagonists: 3,17β-Estradiol 3α-Androstanol 3α-Androstenol 3β-Androstanol 17-Androstanol AITC Ethinylestradiol Meclizine Nigramide J Okadaic acid PK-11195 S-07662 T-0901317
PXRTooltip Pregnane X receptor	Agonists: 17α-Hydroxypregnenolone 17α-Hydroxyprogesterone Δ⁴-Androstenedione Δ⁵-Androstenediol Δ⁵-Androstenedione AA-861 Allopregnanediol Allopregnanedione (5α-dihydroprogesterone) Allopregnanolone (brexanolone) Alpha-Lipoic acid Ambrisentan AMI-193 Amlodipine besylate Antimycotics Artemisinin Aurothioglucose Bile acids Bithionol Bosentan Bumecaine Cafestol Cephaloridine Cephradine Chlorpromazine Ciglitazone Clindamycin Clofenvinfos Chloroxine Clotrimazole Colforsin Corticosterone Cyclophosphamide Cyproterone acetate Demecolcine Dexamethasone DHEA (prasterone) DHEA-S (prasterone sulfate) Dibunate sodium Diclazuril Dicloxacillin Dimercaprol Dinaline Docetaxel Docusate calcium Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl Flucloxacillin Fluorometholone Griseofulvin Guggulsterone Haloprogin Hetacillin potassium Hyperforin Hypericum perforatum (St John's wort) Indinavir sulfate Lasalocid sodium Levothyroxine Linolenic acid: α-Linolenic acid and γ-linolenic acid LOE-908 Loratadine Lovastatin Meclizine Metacycline Methylprednisolone Metyrapone Mevastatin Mifepristone Nafcillin Nicardipine Nicotine Nifedipine Nilvadipine Nisoldipine Norelgestromin Omeprazole Orlistat Oxatomide Paclitaxel Phenobarbital Piperine Plicamycin Prednisolone Pregnanediol Pregnanedione (5β-dihydroprogesterone) Pregnanolone Pregnenolone Pregnenolone 16α-carbonitrile Proadifen Progesterone Quingestrone Reserpine Reverse triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin Tacrolimus Tenylidone Terconazole Testosterone isocaproate Tetracycline Thiamylal sodium Thiothixene Thonzonium bromide Tianeptine Troglitazone Troleandomycin Tropanyl 3,5-dimethulbenzoate Zafirlukast Zeranol Antagonists: Ketoconazole Sesamin
See also Receptor/signaling modulators