KCNH8

KCNH8
Identifiers
Aliases	KCNH8, ELK, ELK1, Kv12.1, elk3, potassium voltage-gated channel subfamily H member 8
External IDs	OMIM: 608260; MGI: 2445160; HomoloGene: 14332; GeneCards: KCNH8; OMA:KCNH8 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	19,535,642 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	53,286,222 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; endothelial cell; ; C1 segment; ; substantia nigra; ; pituitary gland; ; anterior pituitary; ; putamen; ; hippocampus proper; ; testicle; ; amygdala;
	Top expressed in
	otolith organ; ; utricle; ; pituitary gland; ; habenula; ; lumbar spinal ganglion; ; vestibular sensory epithelium; ; Rostral migratory stream; ; ganglionic eminence; ; suprachiasmatic nucleus; ; trigeminal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity; ion channel activity; phosphorelay sensor kinase activity; potassium channel activity; voltage-gated ion channel activity;
Cellular component	integral component of membrane; intracellular anatomical structure; membrane; integral component of plasma membrane; plasma membrane;
Biological process	phosphorelay signal transduction system; regulation of membrane potential; potassium ion transport; regulation of ion transmembrane transport; ion transport; transmembrane transport; signal transduction; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	131096
	211468
	ENSG00000183960
	ENSMUSG00000035580
	Q96L42
	P59111
	NM_144633
	NM_001031811
	NP_653234
	NP_001026981
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily H member 8 is a protein that in humans is encoded by the KCNH8 gene.^[5] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183960 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035580 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

External links

Kv12.1+Potassium+Channel at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
KCNH8+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183960 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035580 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16382104-5] Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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References

Further reading

External links